24-Norursodeoxycholic acid

SKU: orb1310064

Description

Nor-UDCA, a side chain-shortened derivative of ursodeoxycholic acid (UDCA), exhibits enhanced anti-cholestatic, anti-inflammatory, and anti-fibrotic activities. It demonstrates superior efficacy to UDCA in murine models of sclerosing cholangitis, such as Mdr2 knockout mice, making it a valuable research tool for investigating cholestatic liver diseases.

Key Properties

• CAS Number: 99697-24-2
• MW: 378.55
• Purity: 99.69% (May vary between batches)
• Formula: C₂₃H₃₈O₄
• SMILES: [H][C@@]12CC[C@H]([C@H](C)CC(O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@@H](O)C[C@]2([H])C[C@H](O)CC[C@]12C
• Target: Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.57 mM);DMSO:100 mg/mL (264.17 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Norucholic acid, nor-UDCA, Inhibitor, 24 Norursodeoxycholic acid, 24Norursodeoxycholic acid, 24-Norursodeoxycholic acid

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