3-demethylcolchicine

SKU: orb1297034

Description

3-Demethylcolchicine is a bioactive compound isolated from Gloriosa superba. It acts as a tubulin polymerization inhibitor, specifically targeting purified bovine brain tubulin in vitro. This property makes it a valuable tool for studying cytoskeleton dynamics and mitotic disruption in cell biology research.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 7336-33-6
• MW: 385.41
• Purity: 98.24% (May vary between batches)
• Formula: C₂₁H₂₃NO₆
• SMILES: COc1c(O)cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c1OC
• Target: Reactive Oxygen Species,ROS
• Solubility: DMSO:10 mg/mL (25.95 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.59 mM)

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

colchicine, edema, 3-demethylcolchicine, 3demethylcolchicine, 3-Demethylcolchicine, 3 demethylcolchicine, carrageenin, inhibit, Inhibitor, metabolite, radical, Reactive Oxygen Species, ReactiveOxygenSpecies, scavenging

Quick Database Links

Gene Symbol

Reactive Oxygen Species,ROS