3-Methyladenine

SKU: orb1307279

Description

3-Methyladenine (3-MA) is an autophagy inhibitor functioning through the inhibition of class III PI3K VPS34 (IC50=25 μM) and class IB PI3Kγ (IC50=60 μM). It is widely used as a pharmacological tool in both in vitro and in vivo studies to investigate autophagic pathways in cancer, neurodegeneration, and other cellular processes.

Research Area

Cell Biology

Key Properties

• CAS Number: 5142-23-4
• MW: 149.2
• Purity: >98%
• Formula: C₆H₇N₅
• SMILES: Cn1cnc(N)c2ncnc12
• Target: Kinase
• Solubility: Soluble in Water (up to 5 mg/ml), or in DMSO (up to 3 mg/ml), or in DMF (up to 10 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

3-MA

Quick Database Links

Gene Symbol

Kinase