5-Aminosalicylic Acid

SKU: orb1310419

Description

5-Aminosalicylic Acid (5-ASA) is a small molecule acting as a specific PPARγ agonist with additional inhibitory effects on PAK1, NF-κB, and osteopontin. This multi-target activity underpins its utility in research on inflammation and cancer, supported by evidence from both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 89-57-6
• MW: 153.14
• Purity: 97.88% (May vary between batches)
• Formula: C₇H₇NO₃
• SMILES: NC1=CC(C(O)=O)=C(O)C=C1
• Target: PAK,Lipoxygenase,Endogenous Metabolite,NF-κB,Glutathione Peroxidase,COX,PPAR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (21.55 mM);Ethanol:29 mg/mL (189.37 mM);DMSO:80 mg/mL (522.4 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Endogenous Metabolite, COX, 5Aminosalicylic Acid, 5-Aminosalicylic Acid, 5-ASA, 5 Aminosalicylic Acid, ALOX5, PAK, NFkB, NF-kB, NFκB, NF-κB, Nuclear factor-κB, Nuclear factor-kappaB, MPO, inhibit, Glutathione Peroxidase, GlutathionePeroxidase, EndogenousMetabolite, Mesalazine, Mesalamine, Inhibitor, p21 activated kinases, PPARγ, PPAR, Peroxisome proliferator-activated receptors

Quick Database Links

Gene Symbol

PAK,Lipoxygenase,Endogenous Metabolite,NF-κB,Glutathione Peroxidase,COX,PPAR