5-Fluoro-UTP

SKU: orb64970

Description

5-Fluoro-UTP

Images & Validation

• Application Notes:
  Inhibition of viral application; Mutagenic activity; Conformational studies (NMR-NOE) of HIV-2 TAR-RNA; Use as NMR-label (F); X-ray of viral RNA polymerase. ; Spectroscopic Propertie: λmax 267 nm, ε 10.0 L mmol-1 cm-1 (Tris-HCl, pH 7.5).

Key Properties

• CAS Number: 3828-96-4
• MW: Theoretical MW: 502.13 g/mol (free acid); Detected MW: 501.96 g/mol (free acid)
• Purity: ≥ 95% (HPLC)
• Formula: C₉H₁₄N₂O₁₅P₃F
• SMILES: OP(=O)(O)OP(=O)(OP(=O)(OC[C@@H]1[C@H]([C@@H](O)[C@H](n2cc(F)c(=O)[nH]c2=O)O1)O)O)O
• Target: 5-Fluoro-UTP

Storage & Handling

• Storage: Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible.
• Expiration Date: 12 months from date of receipt.
• Hazard Information: Non-Toxic
• Disclaimer: For research use only

Alternative Names

(5F-UTP), 5-Fluoro-uridine-5'-triphosphate, Sodium salt

Chemical Structure of 5F-UTP

Quick Database Links

Gene Symbol

5-Fluoro-UTP

Susanta Chatterjee 1, Parisa Naeli 1, Okan Onar 1 2, Nicole Simms 3, Aitor Garzia 4, Angela Hackett 1, Kelsey Coyle 1, Patric Harris Snell 1, Tom McGirr 1, Tanvi Nitin Sawant 1, Kexin Dang 3, Zornitsa Vasileva Stoichkova 3, Yumna Azam 1, Mark P Saunders 3, Michael Braun 3, Tommy Alain 5, Thomas Tuschl 4, Simon S McDade 1, Daniel B Longley 1, Christos G Gkogkas 6, Colin Adrain 1, John R P Knight 3, Seyed Mehdi Jafarnejad 1 Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil Nucleic Acids Res, (2024)

PubMed: 39351862