7-Epi 10-desacetyl paclitaxel

SKU: orb1301537

Description

7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) is a potent microtubule-stabilizing agent, exhibiting an IC50 of 0.085 nM against HeLa cervical cancer cells in vitro. This taxane derivative is a valuable research tool for studying mechanisms of cytotoxicity and resistance in cancer biology, with applications in both cellular and biochemical assays.

Research Area

Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 78454-17-8
• MW: 811.87
• Purity: 98.05% (May vary between batches)
• Formula: C₄₅H₄₉NO₁₃
• SMILES: [H][C@@]12C[C@@H](O)[C@@]3(C)C(=O)[C@H](O)C4=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c1ccccc1)c1ccccc1
• Target: ADC Cytotoxin
• Solubility: DMSO:8.12 mg/mL (10 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.23 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ADC Cytotoxin, ADCCytotoxin, 7-Epi 10-desacetyl paclitaxel, 7Epi 10desacetyl paclitaxel, 7-Epi-10-deacetyltaxol, 7 Epi 10 desacetyl paclitaxel, 10-Deacetyl-7-epipaclitaxel, Inhibitor, inhibit

Quick Database Links

Gene Symbol

ADC Cytotoxin