A-1210477

SKU: orb1305241

Description

A-1210477 is a potent and selective small molecule dual inhibitor of MCL-1 and Bcl-2, with a Ki of 0.454 nM and an IC50 of 26.2 nM. It is widely used in cancer research, particularly in studies of apoptosis, for both in vitro cellular assays and in vivo xenograft models to investigate hematological malignancies.

Research Area

Cell Biology

Key Properties

• CAS Number: 1668553-26-1
• MW: 850.04
• Purity: 98.89% (May vary between batches)
• Formula: C₄₆H₅₅N₇O₇S
• SMILES: C(CN1CCOCC1)N2C3=C(C=CC=C3C(CCCOC=4C5=C(C=CC4)C=CC=C5)=C2C(O)=O)C6=C(COC7=CC=C(C=C7)N8CCN(S(N(C)C)(=O)=O)CC8)N(C)N=C6C
• Target: Bcl-2 Family,Apoptosis
• Solubility: DMSO:Insoluble;H2O:10 mM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, Bcl-2 Family, A 1210477, A1210477, A-1210477, inhibit, Inhibitor, Mcl-1

Quick Database Links

Gene Symbol

Bcl-2 Family,Apoptosis