A-1331852

SKU: orb1300501

Description

A-1331852 is a potent and selective BCL-XL inhibitor used in cancer research to induce apoptosis in malignant cells. It is applied in studies of hematologic cancers and solid tumors, with utility demonstrated in both in vitro cellular assays and in vivo xenograft models for investigating therapeutic efficacy.

Research Area

Cell Biology

Key Properties

• CAS Number: 1430844-80-6
• MW: 658.81
• Purity: 98.15% (May vary between batches)
• Formula: C₃₈H₃₈N₆O₃S
• SMILES: Cc1c(cnn1CC12CC3CC(CC(C3)C1)C2)-c1ccc(nc1C(O)=O)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1
• Target: Bcl-2 Family
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:150 mg/mL (227.68 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Mcl-1, Inhibitor, inhibit, A1331852, A-1331852, A 1331852, Bcl-2, Bcl-2 Family, Bcl-W, BCL-XL

Quick Database Links

Gene Symbol

Bcl-2 Family