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Acacetin

SKU: orb1224983

Description

Acacetin has anti-plasmodial activity and anti-peroxidant activity. Also acacetin is an ATP-competitive PI3K inhibitor. And has anti-cancer and antitumor activities, such as prostate cancer, melanoma angiogenesis tumor , via Akt/NF-κB,Stat signaling pathway.Has anti-inflammatory and antiarthritic effects in FLSs, can inhibit p38 and JNK phosphorylation and reduces MMP-1, MMP-3 and MMP-13 expression in interleukin-1β-induced FLSs.

Images & Validation

Key Properties

CAS Number480-44-4
MW284.3
Purity>98% (HPLC)
FormulaC16H12O5
SMILESO=C1C=C(C2=CC=C(OC)C=C2)OC3=C1C(O)=CC(O)=C3
TargetCOX
SolubilityDMSO: >10.7mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

LY064233 | NSC 76061

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Acacetin (orb1224983)

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