Agomelatine

SKU: orb1308595

Description

Agomelatine (Valdoxan) is a melatonin analog that acts as a melatonin receptor agonist and a 5-HT2C receptor antagonist. It is widely used in neuroscience research, particularly in studies of depression, circadian rhythms, and sleep disorders, utilizing both in vitro binding assays and in vivo behavioral models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 138112-76-2
• MW: 243.30
• Purity: 99.86% (May vary between batches)
• Formula: C₁₅H₁₇NO₂
• SMILES: COC1=CC=C2C=CC=C(CCNC(C)=O)C2=C1
• Target: Melatonin Receptor,5-HT Receptor,Endogenous Metabolite
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:42 mg/mL (172.63 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.22 mM);DMSO:250 mg/mL (1027.54 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Thymanax, Serotonin Receptor, S 20098, S20098, S-20098, Valdoxan, Melatonin Receptor, MelatoninReceptor, inhibit, Inhibitor, MT1, MT2, 5HTReceptor, 5-HT, 5-hydroxytryptamine Receptor, Agonist, Agomelatine, 5-HT2C, 5-HT Receptor, 5HT Receptor, Antagonist, antidepressant, disorder, depressive

Quick Database Links

Gene Symbol

Melatonin Receptor,5-HT Receptor,Endogenous Metabolite