Ailanthone

SKU: orb1296130

Description

Ailanthone is a natural compound from Ailanthus altissima with potent anti-hepatocellular carcinoma activity. It induces G0/G1 cell cycle arrest via cyclin/CDK downregulation and p21/p27 upregulation and acts as a potent androgen receptor inhibitor. Research applications include in vitro and in vivo studies in oncology, particularly for prostate and liver cancers.

Research Area

Metabolism Research

Key Properties

• CAS Number: 981-15-7
• MW: 376.4
• Purity: 99.71% (May vary between batches)
• Formula: C₂₀H₂₄O₇
• SMILES: [H][C@]12[C@@]3(O)OC[C@@]11[C@@]([H])(C[C@@]4([H])C(C)=CC(=O)[C@@H](O)[C@]24C)OC(=O)C[C@@]1([H])C(=C)[C@H]3O
• Target: Androgen Receptor
• Solubility: DMSO:262.5 mg/mL (697.4 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.77 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Ailanthone, Androgen Receptor, AndrogenReceptor, delta13-Dehydrochaparrinone, Δ13-Dehydrochaparrinone

Quick Database Links

Gene Symbol

Androgen Receptor