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Alizarin

SKU: orb1304810

Description

Alizarin (Mordant Red 11), a natural anthraquinone from madder root, acts as a cytochrome P450 inhibitor with selectivity for CYP1B1 (IC50=2.7 µM) over CYP1A1 and CYP1A2. It is utilized in biochemical research to study the role of these enzymes in xenobiotic metabolism and carcinogenesis in vitro.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Signal Transduction

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Key Properties

CAS Number72-48-0
MW240.21
Purity98.14% (May vary between batches)
FormulaC14H8O4
SMILESOC1=C(O)C2=C(C=C1)C(=O)C1=CC=CC=C1C2=O
TargetCytochromes P450,AMPK,VEGFR,Akt,NF-κB,PI3K
SolubilityH2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:31.6 mg/mL (131.55 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CYP1A1, CYP1A2, CYP1B1, Anthraquinonic, Alizarin, Inhibitor, inhibit, Mordant Red 11

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Alizarin (orb1304810)

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Available Sizes

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1 ml x 10 mM (in DMSO)
$ 80.00
500 mg
$ 80.00
1 g
$ 90.00
DispatchUsually dispatched within 3-5 working days
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