Amsacrine hydrochloride

SKU: orb1301460

Description

Amsacrine hydrochloride is a topoisomerase II inhibitor used in research for acute myelogenous leukemia. It is applied in both in vitro and in vivo studies to investigate mechanisms of cytotoxicity and chemotherapeutic efficacy against hematological cancers.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 54301-15-4
• MW: 429.92
• Purity: 99.05% (May vary between batches)
• Formula: C₂₁H₂₀ClN₃O₃S
• SMILES: Cl.COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12
• Target: Autophagy,Topoisomerase
• Solubility: DMSO:4.3 mg/mL (10 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.33 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Autophagy, Amsacrine, Amsacrine Hydrochloride, Amsacrine hydrochloride, acridinyl anisidide, acridinyl anisidide hydrochloride, acridinyl anisidide Hydrochloride, Inhibitor, inhibit, m-AMSA, m-AMSA Hydrochloride, m-AMSA hydrochloride, Topoisomerase

Quick Database Links

Gene Symbol

Autophagy,Topoisomerase