Anamorelin

SKU: orb1310000

Description

Anamorelin (ONO-7643) is a potent and selective ghrelin receptor agonist, demonstrating an EC50 of 0.74 nM in FLIPR-based assays. It is utilized in research on cancer cachexia, appetite stimulation, and muscle wasting, with applications in both in vitro mechanistic studies and in vivo animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 249921-19-5
• MW: 546.7
• Purity: 99.35% (May vary between batches)
• Formula: C₃₁H₄₂N₆O₃
• SMILES: CN(C)N(C)C(=O)[C@@]1(Cc2ccccc2)CCCN(C1)C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C(C)(C)N
• Target: GHSR
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.66 mM);DMSO:250 mg/mL (457.29 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anamorelin, inhibit, ONO 7643, ONO7643, ONO-7643, Inhibitor, Growth hormone secretagogue receptor, GHSR, GHS-R, ghrelin receptor, RC1291, RC-1291, RC 1291

Quick Database Links

Gene Symbol

GHSR