CD161 Antibody (FITC)

SKU: orb154481

Description

Mouse monoclonal antibody conjugated to FITC which recognizes CD161 that is expressed in a subset of NK cells predominantly in intestinal epithelium and liver that participates in inhibitory role on natural killer (NK) cells cytotoxicity and also plays role as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope.

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: FC
• Reactivity: Rat
• Application Notes:
  Flow cytometry: Recommended dilution: 2-5 μg/ml.

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: Mouse IgG1 kappa
• Clone No.: 10/78
• Immunogen: Splenic cells purified from the LEW rat
• Target: CD161
• Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
• Conjugation: FITC

Storage & Handling

• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Concentration: 0.5 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NKRP1A, Klrb

Separation of rat CD161 positive cells (red-filled) from CD161 negative cells (black-dashed) in flow cytometry analysis of rat splenocyte suspension (surface staining) stained using anti-rat CD161 (10/78) FITC antibody (concentration in sample 1 μg/ml).

Flow cytometry surface staining pattern of rat splenocytes stained using anti-rat CD161 (10/78) FITC antibody (concentration in sample 1 μg/ml).

Quick Database Links

Gene Symbol

CD161

UniProt

Q0ZUP0

NCBI Gene ID

689817