Aplidine

SKU: orb1297925

Description

Aplidine is a potent antiviral agent against SARS-CoV-2 (IC90 = 0.88 nM) and an anti-cancer compound targeting EEF1A2 (Kd = 80 nM). Its applications span oncology and virology research, with studies demonstrating activity in both in vitro cellular assays and in vivo preclinical models.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 137219-37-5
• MW: 1110.34
• Purity: 98.00% (May vary between batches)
• Formula: C₅₇H₈₇N₇O₁₅
• SMILES: [H][C@@]12CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)C(=O)[C@@H](OC(=O)C[C@H](O)[C@]([H])(NC(=O)[C@@H](NC(=O)[C@@H](CC(C)C)N(C)C(=O)[C@@H]1CCCN1C(=O)C(C)=O)[C@@H](C)OC(=O)[C@H](Cc1ccc(OC)cc1)N(C)C2=O)[C@@H](C)CC)C(C)C
• Target: DNA/RNA Synthesis,SARS-CoV
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (2.97 mM);DMSO:50 mg/mL (45.03 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, COVID-19, advanced cancer, Advanced Malignancies, Aplidine, Antiviral, anticancer, infection, inhibit, Inhibitor, MOLT-4, Plitidepsin, Leukemia, EEF1A2, SARS-CoV, SARS-CoV-2, SARS coronavirus, SARSCoV, RNA Synthesis, RNASynthesis, VEGF

Quick Database Links

Gene Symbol

DNA/RNA Synthesis,SARS-CoV