Arenobufagin

SKU: orb1301359

Description

Arenobufagin is a bufadienolide compound isolated from toad venom. It exhibits potent antineoplastic activity against hepatocellular carcinoma HepG2 cells and their multidrug-resistant HepG2/ADM counterparts in vitro. This natural product is a valuable research tool for studying cancer cell apoptosis and overcoming drug resistance mechanisms.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 464-74-4
• MW: 416.51
• Purity: 99.14% (May vary between batches)
• Formula: C₂₄H₃₂O₆
• SMILES: C[C@@]12[C@H](CC[C@]1(O)[C@@H]1CC[C@@H]3C[C@@H](O)CC[C@]3(C)[C@H]1[C@H](O)C2=O)c1ccc(=O)oc1
• Target: Others,mTOR,ATG,Akt,PARP,Apoptosis,Caspase,Autophagy,PI3K
• Solubility: DMSO:250 mg/mL (600.23 mM);Ethanol:10 mg/mL (24.01 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Arenobufagin

Quick Database Links

Gene Symbol

Others,mTOR,ATG,Akt,PARP,Apoptosis,Caspase,Autophagy,PI3K