Aripiprazole

SKU: orb1226597

Description

Aripiprazole(Abilify) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.(In Vitro):Aripiprazole potently activates D2 receptor-mediated inhibition of cAMP accumulation.Aripiprazole shows a greater anti-inflammatory effect on TNF-α, IL-13, IL-17α and fractalkine.(In Vivo):Aripiprazole (0-3 mg/kg, IP, daily) shows some anxiolytic properties.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 129722-12-9
• MW: 448.39
• Purity: >98% (HPLC)
• Formula: C₂₃H₂₇Cl₂N₃O₂
• SMILES: C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
• Target: 5-HT Receptor
• Solubility: DMSO: 90 mg/mL (200.71 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

OPC 31 | OPC 14597

Quick Database Links

Gene Symbol

5-HT Receptor