AS-8351

SKU: orb1303162

Description

AS8351 (NSC51355) is a histone demethylase inhibitor. It has been utilized in cellular reprogramming research, notably in combination with other small molecules to convert human fetal lung fibroblasts into cardiomyocyte-like cells in vitro, demonstrating its role in epigenetic regulation and cardiac regeneration studies.

Research Area

Epigenetics & Chromatin, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 796-42-9
• MW: 291.3
• Purity: >98%
• Formula: C₁₇H₁₃N₃O₂
• SMILES: NN(\C=C1/C(=O)C=Cc2ccccc12)C(=O)c1ccncc1
• Target: Protein demethylase
• Solubility: Soluble in DMSO (up to 45 mg/ml), in DMF (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NSC-51355

Quick Database Links

Gene Symbol

Protein demethylase