Asimadoline

SKU: orb1222652

Description

Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis. Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. It has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases.

Key Properties

• CAS Number: 153205-46-0
• MW: 414.54
• Purity: >98% (HPLC)
• Formula: C₂₇H₃₀N₂O₂
• SMILES: CN([C@H](CN1CC[C@@H](C1)O)C2=CC=CC=C2)C(=O)C(C3=CC=CC=C3)C4=CC=CC=C4
• Target: DNA/RNA Synthesis
• Solubility: DMSO : ≥ 103.3 mg/mL; 249.19 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Asimadoline

Quick Database Links

Gene Symbol

DNA/RNA Synthesis