Astragaloside IV

SKU: orb1304786

Description

Astragaloside IV is a bioactive saponin from Astragalus membranaceus with broad research applications. It exhibits anti-cancer activity in vitro by inhibiting ERK/JNK signaling and MMPs in MDA-MB-231 cells, and demonstrates cardioprotective effects in vivo, reducing infarct size in canine models. It also shows antiviral activity against HAdV-3 replication in A549 cells.

Research Area

Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 84687-43-4
• MW: 784.97
• Purity: 98.85% (May vary between batches)
• Formula: C₄₁H₆₈O₁₄
• SMILES: CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]1[C@H](O)C[C@@]2(C)C3C[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C4[C@]5(CC35CC[C@]12C)CCC(O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)C4(C)C
• Target: MMP,Estrogen/progestogen Receptor,ERK,JNK
• Solubility: DMSO:100 mg/mL (127.39 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AS-IV, Astragaloside IV, AST-IV, Matrix metalloproteinases, ERS, ERK, Extracellular signal regulated kinases, Estrogen Receptor, EstrogenReceptor, MMP, Inhibitor, inhibit, JNK, progestogen Receptor, progestogenReceptor

Quick Database Links

Gene Symbol

MMP,Estrogen/progestogen Receptor,ERK,JNK