Auranofin

SKU: orb1309052

Description

Auranofin is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 µM. This antirheumatic agent, used for rheumatoid arthritis, has demonstrated antiviral activity against SARS-CoV-2 in vitro and has been investigated in various cancer and infectious disease research models.

Research Area

Cell Biology, Neuroscience, Protein Biochemistry

Key Properties

• CAS Number: 34031-32-8
• MW: 678.49
• Purity: >98%
• Formula: C₂₀H₃₄AuO₉PS
• SMILES: O(C(C)=O)[C@@H]1[C@@H](OC(C)=O)[C@H]([S-][Au+][P](CC)(CC)CC)O[C@H](COC(C)=O)[C@H]1OC(C)=O
• Target: Kinase
• Solubility: Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 4 mg/ml).

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SKF-39162

Quick Database Links

Gene Symbol

Kinase