Avatrombopag

SKU: orb1299838

Description

Avatrombopag is a small molecule thrombopoietin receptor agonist that stimulates megakaryocyte growth and platelet production. It is widely used in research for studying thrombocytopenia, with applications in both in vitro cellular assays and in vivo animal models to investigate hematopoiesis and platelet disorders.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 570406-98-3
• MW: 649.65
• Purity: 99.01% (May vary between batches)
• Formula: C₂₉H₃₄Cl₂N₆O₃S₂
• SMILES: OC(=O)C1CCN(CC1)c1ncc(cc1Cl)C(=O)Nc1nc(-c2cc(Cl)cs2)c(s1)N1CCN(CC1)C1CCCCC1
• Target: Thrombin,Thrombopoietin Receptor
• Solubility: DMSO:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

E5501, E-5501, E 5501, Avatrombopag, AKR 501, AKR501, AKR-501, mimic, NOD/SCID, inhibit, megakaryocytes, megakaryocytopoiesis, Inhibitor, YM 477, YM477, YM-477, proliferation, phosphorylation, Thrombopoietin Receptor, ThrombopoietinReceptor, TPO

Quick Database Links

Gene Symbol

Thrombin,Thrombopoietin Receptor