AZ876

SKU: orb1302023

Description

AZ876 is a potent and selective liver X receptor (LXR) agonist, demonstrating high affinity for both human LXRα (Ki/EC50 = 7/6 nM) and LXRβ (Ki/EC50 = 11/73 nM). This small molecule is a valuable research tool for studying LXR-mediated pathways in atherosclerosis, lipid metabolism, and inflammation in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 898800-26-5
• MW: 439.57
• Purity: 99.41% (May vary between batches)
• Formula: C₂₄H₂₉N₃O₃S
• SMILES: CC(C)(C)N1C(=O)C(Nc2ccc(cc2)N2CCCCC2)=C(c2ccccc2)S1(=O)=O
• Target: Liver X Receptor
• Solubility: DMSO:55 mg/mL (125.12 mM);5% DMSO+40% PEG300+5% Tween 80+50% Saline:2.5 mg/mL (5.69 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AZ 876, AZ-876, AZ876, LXR, inhibit, Liver X Receptor, LiverXReceptor, Liver X receptor, Inhibitor

Quick Database Links

Gene Symbol

Liver X Receptor