AZD9496

SKU: orb1303489

Description

AZD9496 is an orally bioavailable, selective antagonist of estrogen receptor alpha (ERα) with potential antitumor activity. It has demonstrated efficacy in inhibiting the growth of ER-positive breast cancer cells in vitro and in xenograft models in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1639042-08-2
• MW: 442.47
• Purity: 97.28% (May vary between batches)
• Formula: C₂₅H₂₅F₃N₂O₂
• SMILES: C(C(C)(C)F)N1[C@@H](C2=C(C=3C(N2)=CC=CC3)C[C@H]1C)C4=C(F)C=C(/C=C/C(O)=O)C=C4F
• Target: Estrogen/progestogen Receptor,Estrogen Receptor/ERR
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:125 mg/mL (282.51 mM);Ethanol:82 mg/mL (185.32 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.46 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AZD9496, AZD-9496, AZD 9496, inhibit, Inhibitor, Estrogen Receptor, Estrogen Receptor/ERR, EstrogenReceptor, ERα, ERR, progestogen Receptor, progestogenReceptor

Quick Database Links

Gene Symbol

Estrogen/progestogen Receptor,Estrogen Receptor/ERR