Baricitinib

SKU: orb1305415

Description

Baricitinib is an orally active, selective inhibitor of JAK1 and JAK2. It is widely used in research for its immunomodulatory and anti-inflammatory properties, with applications in studying autoimmune diseases and hematological cancers in both in vitro and in vivo models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1187594-09-7
• MW: 371.42
• Purity: 99.00% (May vary between batches)
• Formula: C₁₆H₁₇N₇O₂S
• SMILES: CCS(=O)(=O)N1CC(CC#N)(C1)n1cc(cn1)-c1[nH]cnc2nccc12
• Target: Chk,Tyrosine Kinases,JAK
• Solubility: H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: < 1 mg/mL (insoluble or slightly soluble) DMSO: 250 mg/mL (673.09 mM), Sonication is recommended.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Chk2, Baricitinib, INCB028050, INCB-028050, INCB 028050, Janus kinase, JAK1, JAK2, JAK3, JAK, inhibit, Inhibitor, LY3009104, LY-3009104, LY 3009104, Tyk2, TyrosineKinases, Tyrosine Kinases

Quick Database Links

Gene Symbol

Chk,Tyrosine Kinases,JAK