Bemnifosbuvir hemisulfate

SKU: orb1298178

Description

Bemnifosbuvir hemisulfate (AT-527) is a direct-acting antiviral nucleotide prodrug that potently inhibits hepatitis C virus (HCV) replication. It has demonstrated antiviral activity in both in vitro assays and in vivo clinical studies, making it a valuable tool for HCV research.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• CAS Number: 2241337-84-6
• MW: 1261.15
• Purity: 99.74% (May vary between batches)
• Formula: C₄₈H₆₈F₂N₁₄O₁₈P₂S
• SMILES: C[C@@H](C(OC(C)C)=O)N[P@@](OC1=CC=CC=C1)(OC[C@H]2O[C@@H](N3C=NC4=C(NC)N=C(N)N=C34)[C@](C)(F)[C@@H]2O)=O.C[C@@H](C(OC(C)C)=O)N[P@@](OC5=CC=CC=C5)(OC[C@H]6O[C@@H](N7C=NC8=C(NC)N=C(N)N=C78)[C@](C)(F)[C@@H]6O)=O.O=S(O)(O)=O
• Target: SARS-CoV,HCV Protease
• Solubility: DMSO:170 mg/mL (134.8 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (3.96 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bemnifosbuvir, Bemnifosbuvir hemisulfate, Bemnifosbuvir Hemisulfate, antiviral, AT 527, AT527, AT-527, HCVProtease, HCV, HCV Protease, Hepatitis C virus, guanosine, Inhibitor, inhibit, pangenotypic, nucleotide, phosphoramidate, SARS coronavirus, SARSCoV, SARS-CoV, SARS-CoV-2

Quick Database Links

Gene Symbol

SARS-CoV,HCV Protease