Berberine

SKU: orb1302341

Description

Berberine (Umbellatine) is a bioactive alkaloid known to activate AMPK, inhibit topoisomerase, and induce ROS. Its broad research applications include studying anti-tumor, antimicrobial, and metabolic effects in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 2086-83-1
• MW: 336.36
• Purity: 95.71% (May vary between batches)
• Formula: C₂₀H₁₈NO₄
• SMILES: O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC
• Target: Parasite,Topoisomerase,Antibacterial,Akt,Antibiotic,ROS,Reactive Oxygen Species,NF-κB,Apoptosis,Endogenous Metabolite,Caspase,Autophagy,JNK,DNA/RNA Synthesis,PI3K
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.05 mg/mL (6.09 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;DMSO:9.8 mg/mL (29.14 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Natural Yellow 18, Natural Yellow18, Natural Yellow-18, inhibit, Inhibitor, Endogenous Metabolite, EndogenousMetabolite, Berberin, Berberine, Bacterial, Autophagy, Antibacterial, Antibiotic, Reactive Oxygen Species, ReactiveOxygenSpecies, Topoisomerase, Umbellatine

Quick Database Links

Gene Symbol

Parasite,Topoisomerase,Antibacterial,Akt,Antibiotic,ROS,Reactive Oxygen Species,NF-κB,Apoptosis,Endogenous Metabolite,Caspase,Autophagy,JNK,DNA/RNA Synthesis,PI3K