BFH772

SKU: orb1304013

Description

BFH772 is a potent and selective small-molecule VEGF inhibitor, structurally analogous to BAW2881. It primarily targets VEGFR2 kinase with high potency (IC50 = 3 nM) and also inhibits RET, PDGFR, and KIT autophosphorylation. This profile supports its research use in angiogenesis, oncology, and related in vitro and in vivo studies.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 890128-81-1
• MW: 439.39
• Purity: 97.71% (May vary between batches)
• Formula: C₂₃H₁₆F₃N₃O₃
• SMILES: OCc1cc(Oc2ccc3c(cccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1
• Target: VEGFR
• Solubility: 10% DMSO+90% Corn Oil:3.3 mg/mL (7.51 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:81 mg/mL (184.35 mM);DMSO:81 mg/mL (184.35 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BFH 722, BFH 772, BFH722, BFH-722, BFH772, BFH-772, Inhibitor, inhibit, VEGFR2, VEGFR, Vascular endothelial growth factor receptor

Quick Database Links

Gene Symbol

VEGFR