BGT226

SKU: orb1301099

Description

BGT226 (NVP-BGT226) is a potent dual inhibitor of PI3K and mTOR, demonstrating high potency against PI3Kα, β, and γ isoforms. It is utilized in preclinical research to investigate oncogenic signaling pathways and has been studied in various cancer cell lines and in vivo tumor models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 915020-55-2
• MW: 534.53
• Purity: 95.74% (May vary between batches)
• Formula: C₂₈H₂₅F₃N₆O₂
• SMILES: COc1ccc(cn1)-c1ccc2ncc3n(C)c(=O)n(-c4ccc(N5CCNCC5)c(c4)C(F)(F)F)c3c2c1
• Target: PI3K,Autophagy,mTOR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.87 mM);DMSO:65 mg/mL (121.6 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PI3K, PI3Kγ, PI3Kβ, PI3Kα, Autophagy, BGT 226, BGT226, BGT-226, BGT226 free base, mTOR, NVP-BGT 226, NVP-BGT226, NVP-BGT-226, Mammalian target of Rapamycin

Quick Database Links

Gene Symbol

PI3K,Autophagy,mTOR