Bigelovin

SKU: orb1218100

Description

Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a potent cytotoxic sesquiterpene lactone from Inula sp.

Key Properties

• CAS Number: 3668-14-2
• MW: 304.34
• Purity: >98% (HPLC)
• Formula: C₁₇H₂₀O₅
• SMILES: C[C@H](C[C@@H]([C@H]([C@@H]([C@]12C)OC(C)=O)C3=C)OC3=O)[C@@H]2C=CC1=O
• Target: Apoptosis
• Solubility: In Vitro: DMSO : 100 mg/mL (328.58 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis