BML-284

SKU: orb1304496

Description

BML-284 (Wnt agonist 1) is a cell-permeable, selective small molecule that potently activates Wnt/β-catenin signaling. It is widely used in vitro to study stem cell biology, tissue regeneration, and oncogenesis, and has been applied in vivo within bone and cartilage research models.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 853220-52-7
• MW: 350.37
• Purity: 99.66% (May vary between batches)
• Formula: C₁₉H₁₈N₄O₃
• SMILES: COc1cccc(c1)-c1cc(NCc2ccc3OCOc3c2)nc(N)n1
• Target: Wnt/beta-catenin
• Solubility: DMSO:255 mg/mL (727.8 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.71 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

betacatenin, beta-catenin, AGS, BML 284, BML284, BML-284, bcatenin, cardiac defect, E-cadherin, Inhibitor, malformed phenotype, inhibit, N-cadherin, MNK45, Wnt agonist 1, Wnt, Wnt/betacatenin, Wnt/b-catenin, Wnt/β-catenin, TCF, βcatenin

Quick Database Links

Gene Symbol

Wnt/beta-catenin