BRD3308

SKU: orb1299101

Description

BRD3308 is a potent and selective HDAC3 inhibitor with an IC50 of 54 nM. It specifically reduces phenylephrine-induced ERK phosphorylation without affecting JNK, making it a valuable chemical probe for studying HDAC3 function in cardiac hypertrophy and fibrosis research in vitro.

Research Area

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 1550053-02-5
• MW: 287.29
• Purity: 97.00% (May vary between batches)
• Formula: C₁₅H₁₄FN₃O₂
• SMILES: CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N
• Target: Apoptosis,HDAC,HIV Protease
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.96 mM);DMSO:52 mg/mL (181 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

β-cells, inflammatory, inhibit, Inhibitor, hyperglycaemia, Human immunodeficiency virus, insulin, HDAC, HDAC3, HIV, HIV Protease, HIVProtease, HIV-1, Histone deacetylases, latency, glucolipotoxicity, Apoptosis, diabetes, cytokines, BRD3308, BRD-3308, BRD 3308

Quick Database Links

Gene Symbol

Apoptosis,HDAC,HIV Protease