Brefeldin A

SKU: orb1301107

Description

Brefeldin A is a macrolide antibiotic and potent ATPase inhibitor that induces tumor cell differentiation and apoptosis while also inhibiting autophagy. It is widely used in cancer research to study intracellular transport mechanisms in both cellular and animal models.

Research Area

Cell Biology

Key Properties

• CAS Number: 20350-15-6
• MW: 280.4
• Purity: >98%
• Formula: C₁₆H₂₄O₄
• SMILES: [H][C@@]12C[C@H](O)C[C@@]1([H])[C@H](O)\C=C\C(=O)O[C@@H](C)CCC\C=C\2
• Target: ER/Golgi
• Solubility: Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 25 mg/ml).

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cas9, Brefeldin A, Cyanein, CRISPR/Cas9, CRISPR, Decumbin, BFA, Ascotoxin, ATPase (HCT 116), Autophagy, Antibiotic, inhibit, Mitochondrial Autophagy, Mitophagy, Inhibitor, Herpes simplex virus, HSV

Quick Database Links

Gene Symbol

ER/Golgi