BRL 54443

SKU: orb1305455

Description

BRL 54443 is a selective and high-affinity agonist for the 5-HT1E and 5-HT1F receptors, with pKi values of 8.7 and 8.9, respectively. It is a valuable research tool for investigating serotonin receptor function in models of migraine and neuropathic pain, both in vitro and in vivo.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 57477-39-1
• MW: 230.31
• Purity: 98.07% (May vary between batches)
• Formula: C₁₄H₁₈N₂O
• SMILES: OC=1C=C2C(=CNC2=CC1)C3CCN(C)CC3
• Target: 5-HT Receptor
• Solubility: DMSO:43 mg/mL (186.7 mM);Ethanol:2 mg/mL (8.68 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.68 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BRL 54443, BRL54443, BRL-54443, 5-hydroxytryptamine Receptor, 5HTReceptor, 5HT Receptor, 5-HT Receptor, 5-HT1E, 5-HT1F, 5-HT1D, 5-HT1B, 5-HT1A, Inhibitor, inhibit, Serotonin Receptor

Quick Database Links

Gene Symbol

5-HT Receptor