Bufarenogin

SKU: orb1297437

Description

Bufarenogin is a bufadienolide compound isolated from the Cuban toad _Peltophryne fustiger_. This natural product exhibits anti-tumor activity and has been investigated in vitro for its cytotoxic effects against various cancer cell lines.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 17008-65-0
• MW: 416.51
• Purity: 98.21% (May vary between batches)
• Formula: C₂₄H₃₂O₆
• SMILES: C[C@@]12[C@@](O)([C@]3([C@](C(=O)[C@H]1O)([C@]4(C)[C@](CC3)(C[C@@H](O)CC4)[H])[H])[H])CC[C@@H]2C=5C=CC(=O)OC5
• Target: MEK,PI3K,Bcl-2 Family,ERK,Apoptosis
• Solubility: DMSO:50 mg/mL (120.05 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.8 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PI3K, MEK, ERK, Bufarenogin, 3beta,12beta,14-Trihydroxy-11-oxo-5beta-bufa-20,22-dienolide

Quick Database Links

Gene Symbol

MEK,PI3K,Bcl-2 Family,ERK,Apoptosis