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(-)-Butin

SKU: orb1297436

Description

(-)-Butin is a natural flavonoid with potent antioxidant properties. It activates the Nrf2 pathway via PI3K/Akt signaling to upregulate MnSOD, thereby protecting cells from H2O2-induced apoptosis and mitochondrial dysfunction in vitro. This mechanism supports its research in models of oxidative stress-related diseases.

Research Area

Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number492-14-8
MW272.25
Purity98.07% (May vary between batches)
FormulaC15H12O5
SMILESOc1ccc2C(=O)C[C@H](Oc2c1)c1ccc(O)c(O)c1
TargetPI3K,Akt,Nrf2
SolubilityDMSO:50 mg/mL (183.65 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.69 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Butin, Akt, ( ) Butin, ()Butin, inhibit, Nrf2, Inhibitor, PI3K

Similar Products

  • (-)-Butin [orb1217978]

    >98% (HPLC)

    492-14-8

    272.25

    C15H12O5

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Protocol Information

(-)-Butin (orb1297436)

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Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 200.00
1 ml x 10 mM (in DMSO)
$ 210.00
10 mg
$ 260.00
25 mg
$ 420.00