BX430

SKU: orb1308509

Description

BX430 is a potent, selective, and species-specific noncompetitive allosteric antagonist of human P2X4 receptor channels (IC₅₀ = 0.54 µM). It serves as a valuable research tool for investigating the role of P2X4 in pathologies such as chronic pain and cardiovascular disease, with utility in both in vitro and in vivo experimental models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 688309-70-8
• MW: 413.11
• Purity: 97.34% (May vary between batches)
• Formula: C₁₅H₁₅Br₂N₃O
• SMILES: CC(C)c1cc(Br)c(NC(=O)Nc2cccnc2)c(Br)c1
• Target: Calcium Channel,P2X Receptor
• Solubility: DMSO:30 mg/mL (72.62 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.84 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

P2X Receptor, P2X4, P2XReceptor, P2XRs, receptor, specificity, species, Inhibitor, human P2X4 receptor channels, human, pain, inhibit, Ca channels, BX 430, BX430, BX-430, cardiovascular, Calcium Channel, Ca2+ channels, channels, CalciumChannel, chronic, disease

Quick Database Links

Gene Symbol

Calcium Channel,P2X Receptor