Carnosol

SKU: orb1300224

Description

Carnosol is a small molecule that activates the Nrf2 pathway, elevating heme oxygenase 1 (HMOX1) expression, and inhibits ribosomal S6 kinase 2 (RSK2). It is utilized in research areas such as gastric cancer, with studies demonstrating its activity in both cellular and animal models of oxidative stress and inflammation.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 5957-80-2
• MW: 330.42
• Purity: >98%
• Formula: C₂₀H₂₆O₄
• SMILES: CC(C)c1cc2[C@H]3C[C@H]4C(C)(C)CCC[C@@]4(C(=O)O3)c2c(O)c1O
• Target: Antioxidant
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.05 mM);DMSO:60 mg/mL (181.59 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Endogenous Metabolite, Carnosol, EndogenousMetabolite, Inhibitor, Keap1-Nrf2, inhibit, Ribosomal S6 Kinase (RSK), RSK2, S6K, S6Kinase, S6 Kinase

Quick Database Links

Gene Symbol

Antioxidant