Catalpol

SKU: orb1225547

Description

Catalpol, an iridoid glycoside, has neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.(In Vitro):Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length.(In Vivo):Catalpol (25-100 mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities.

Key Properties

• CAS Number: 2415-24-9
• MW: 362.33
• Purity: >98% (HPLC)
• Formula: C₁₅H₂₂O₁₀
• SMILES: [H][C@]1([C@H](O)[C@@]2([H])[C@]3(CO)O2)[C@]3([H])[C@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)OC=C1
• Target: Others
• Solubility: DMSO: 10 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Catalpinoside | 7,8-epoxy Aucubin

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