CCCP

SKU: orb1300092

Description

CCCP is a mitochondrial uncoupler that dissipates the proton gradient, inhibiting oxidative phosphorylation. It is widely used in vitro to study mitochondrial function, cellular metabolism, and innate immunity, as it also suppresses the STING-TBK1-IRF3 signaling pathway.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 555-60-2
• MW: 204.62
• Purity: 97.15% (May vary between batches)
• Formula: C₉H₅ClN₄
• SMILES: ClC1=CC=CC(N\N=C(/C#N)C#N)=C1
• Target: PTEN,Antibacterial,IFNAR,STING,COX,Apoptosis,OXPHOS,IκB/IKK,Mitochondrial Metabolism
• Solubility: Ethanol:5 mg/mL (24.44 mM);DMSO:252.5 mg/mL (1233.99 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:6 mg/mL (29.32 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CCCP, Apoptosis, Bacterial, Carbonyl Cyanide m-Chlorophenylhydrazone, Carbonyl cyanide 3-chlorophenylhydrazone, MPYS, IkB, IkB/IKK, IKK, IκB, inhibit, MitochondrialMetabolism, MITA, Mitochondrial Metabolism, ERIS, IFN-β, IFNAR, Inhibitor, Interferon-α/β receptor, Interferon-alpha/beta receptor, TBK1, Stimulator of Interferon Genes, STING, TMEM173

Quick Database Links

Gene Symbol

PTEN,Antibacterial,IFNAR,STING,COX,Apoptosis,OXPHOS,IκB/IKK,Mitochondrial Metabolism