CGS 21680 Hydrochloride

SKU: orb1300765

Description

CGS 21680 HCl is a potent and highly selective adenosine A2A receptor agonist (IC50=22 nM), exhibiting 140-fold selectivity for A2A over A1 receptors. It is widely used in vitro and in vivo to study adenosine signaling, neuroprotection, inflammation, and cardiovascular models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 124431-80-7
• MW: 535.98
• Purity: 96.74% (May vary between batches)
• Formula: C₂₃H₂₉N₇O₆·HCl
• SMILES: Cl.CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(NCCc3ccc(CCC(O)=O)cc3)nc12
• Target: Adenosine Receptor
• Solubility: DMSO:53.6 mg/mL (100 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.73 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, CGS 21680, CGS 21680 HCl, CGS 21680 Hydrochloride, CGS21680, CGS-21680, CGS21680 Hydrochloride, CGS-21680 Hydrochloride, A2, Adenosine Receptor, AdenosineReceptor, P1 receptor

Quick Database Links

Gene Symbol

Adenosine Receptor