Chebulinic acid

SKU: orb1296148

Description

Chebulinic acid is a multi-target small molecule that potently inhibits Mycobacterium tuberculosis DNA gyrase and also blocks SMAD-3 phosphorylation and H+ K+-ATPase activity. This makes it a valuable research tool for studies in bacteriology, oncology, and gastroenterology, applicable in both in vitro enzymatic assays and cellular research.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 18942-26-2
• MW: 956.68
• Purity: 98.40% (May vary between batches)
• Formula: C₄₁H₃₂O₂₇
• SMILES: OC1C2C(CC(O)=O)C(=O)OC3C(COC(=O)c4cc(O)c(O)c(O)c4)OC(OC(=O)c4cc(O)c(O)c(O)c4)C(OC(=O)c4cc(O)c(O)c(OC1=O)c24)C3OC(=O)c1cc(O)c(O)c(O)c1
• Target: Proton pump,DNA/RNA Synthesis,Antibacterial,ATPase,TGF-beta/Smad
• Solubility: DMSO:130 mg/mL (135.89 mM);H2O:<1 mg/mL (insoluble)

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, H+/K+-ATPase, bacterial DNA gyrase, DNASynthesis, DNA/RNA Synthesis, DNA Synthesis, Chebulinic acid, Protonpump, Proton pump, Proton Pump, TGFb, TGF-b/Smad, TGF-beta/Smad, TGF-beta, TGFbeta, TGFbeta/Smad, TGFβ, TGF-β/Smad, Transforming growth factor beta, Smad, Smad3, RNASynthesis, RNA Synthesis

Quick Database Links

Gene Symbol

Proton pump,DNA/RNA Synthesis,Antibacterial,ATPase,TGF-beta/Smad