CHIR-98014

SKU: orb1305269

Description

CHIR-98014 is a potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor. It enhances insulin-stimulated glucose uptake and metabolism in both cellular and animal models, making it a valuable research tool for studying diabetes, insulin resistance, and Wnt/β-catenin signaling pathways.

Research Area

Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 252935-94-7
• MW: 486.31
• Purity: 97.09% (May vary between batches)
• Formula: C₂₀H₁₇Cl₂N₉O₂
• SMILES: ClC1=C(C=2C(=CN=C(NCCNC=3N=C(N)C(N(=O)=O)=CC3)N2)N4C=CN=C4)C=CC(Cl)=C1
• Target: FGFR,Src,S6 Kinase,GSK-3
• Solubility: DMSO:4.87 mg/mL (10.01 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

bFGFR, CT98014, CT 98014, c-Src, CT-98014, CHIR 98014, CHIR-98014, CHIR98014, p70 S6K, inhibit, Inhibitor, Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK-3β, GSK-3α, GSK3, GSK-3, S6 Kinase, S6Kinase

Quick Database Links

Gene Symbol

FGFR,Src,S6 Kinase,GSK-3