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CITCO

SKU: orb1218138

Description

CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it also is a selective Constitutive androstane receptor (CAR) agonist.

Images & Validation

Key Properties

CAS Number338404-52-7
MW436.74
Purity>98% (HPLC)
FormulaC19H12Cl3N3OS
SMILESClc(cc1)ccc1-c1c(/C=N/OCc(cc2)cc(Cl)c2Cl)n(ccs2)c2n1
TargetCAR|PXR
SolubilityDMSO:soluble; H2O:insoluble

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    99.24% (May vary between batches)

    338404-52-7

    436.74

    C19H12Cl3N3OS

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CITCO (orb1218138)

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