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CL 218872

SKU: orb1219946

Description

CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo.

Images & Validation

Key Properties

CAS Number66548-69-4
MW278.23
Purity>98% (HPLC)
FormulaC13H9F3N4
SMILESCc1nnc2ccc(nn12)-c1cccc(c1)C(F)(F)F
TargetGABAA
SolubilityDMSO:13.9 mg/mL (50 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • CL 218872 [orb1298821]

    99.92% (May vary between batches)

    66548-69-4

    278.23

    C13H9F3N4

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CL 218872 (orb1219946)

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