CL097

SKU: orb1303677

Description

CL097 is a potent dual agonist of TLR7 and TLR8, known to trigger pro-inflammatory cytokine release and prime NADPH oxidase in macrophages. This priming enhances fMLF-stimulated reactive oxygen species (ROS) production, making it a valuable tool for studying innate immune responses, inflammation, and oxidative burst mechanisms in both cellular and animal models.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1026249-18-2
• MW: 242.28
• Purity: 99.57% (May vary between batches)
• Formula: C₁₃H₁₄N₄O
• SMILES: CCOCc1nc2c([nH]1)c(N)nc1ccccc21
• Target: TLR,Reactive Oxygen Species,ROS
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (13.62 mM);DMSO:95 mg/mL (392.11 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Heterocycle, Inhibitor, Immunological, inhibit, Oligonucleotide, modulators, CL 097, CL097, CL-097, Peptide, Reactive Oxygen Species, TLR8, TLR7, ReactiveOxygenSpecies, Toll-like Receptor (TLR)

Quick Database Links

Gene Symbol

TLR,Reactive Oxygen Species,ROS