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Clomethiazole

SKU: orb1308439

Description

Clomethiazole (Distraneurin) is an orally active anticonvulsant and GABAA receptor agonist, researched for potential use in status epilepticus. It is also employed in vitro as a selective inhibitor of human cytochrome P450 isoforms CYP2A6 and CYP2E1 in metabolic studies.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number533-45-9
MW161.65
Purity98.43% (May vary between batches)
FormulaC6H8ClNS
SMILESCl.CC1=C(CCCl)SC=N1
TargetGABA Receptor,Cytochromes P450
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (30.93 mM);DMSO:240 mg/mL (1484.69 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

insomnia, Inhibitor, GABAReceptor, GABAA, GABA Receptor, Gamma-aminobutyric acid Receptor, inhibit, neuroprotective, anticonvulsant, alcoholism, 5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE, CYP2E1, CYP2A6, CYPs, Cytochrome P450, Distraneurin, Clomethiazole, Chlormethiazole, sedative, γ-Aminobutyric acid Receptor

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Clomethiazole (orb1308439)

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Available Sizes

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1 ml x 10 mM (in DMSO)
$ 90.00
100 mg
$ 90.00
200 mg
$ 100.00
500 mg
$ 140.00
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