COH-SR4

SKU: orb1298671

Description

COH-SR4 is a mitochondrial oxidative phosphorylation uncoupler that inhibits hepatocellular carcinoma cell proliferation by modulating the AMPK-mTOR signaling pathway. It serves as a research tool for studying cancer metabolism and has demonstrated anti-proliferative effects in in vitro models like HepG2 cells.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 73439-19-7
• MW: 350.03
• Purity: 98.96% (May vary between batches)
• Formula: C₁₃H₈Cl₄N₂O
• SMILES: Clc1cc(Cl)cc(NC(=O)Nc2cc(Cl)cc(Cl)c2)c1
• Target: AMPK
• Solubility: DMSO:4 mg/mL (11.43 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

leukemia, melanoma, Inhibitor, lung, inhibit, kinase, Mitochondria uncoupler SR4, AMP-activated protein kinase, anti-proliferative, AMP-activated, AMPK, anticancer, anti-adipogenic, cancers, breast, COH SR4, COHSR4, COH-SR4, COH-SR-4, COH-SR4 (Mitochondria uncoupler SR4), protein

Quick Database Links

Gene Symbol

AMPK