Col003

SKU: orb1309817

Description

Col003 is a potent and selective Hsp47 inhibitor that competitively targets its collagen-binding site with an IC50 of 1.8 µM. This small molecule is a valuable research tool for studying fibrosis mechanisms in both cellular and animal models.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 328565-16-8
• MW: 257.24
• Purity: 98.67% (May vary between batches)
• Formula: C₁₄H₁₁NO₄
• SMILES: Oc1c(C=O)cc(Cc2ccccc2)cc1[N+]([O-])=O
• Target: HSP
• Solubility: DMSO:188 mg/mL (730.84 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.77 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

structure, triple, Col 003, Col003, Col-003, collagen, Hsp47, HSP47, HSP, Inhibitor, interaction, Heat shock proteins, helix, MEF, inhibit, secretion

Quick Database Links

Gene Symbol

HSP